ABSTRACT
<p><b>OBJECTIVE</b>To study the chemical constituents of Ligularia intermedia of Shanxi.</p><p><b>METHOD</b>The compounds were isolated by column chromatography on silica gel and preparative TLC. The structures were identified by IR, MS, 1D/2DNMR spectral data and X-ray single crystal diffraction and other methods1.</p><p><b>RESULT</b>Nine compound were isolated and identified as 8beta-hydroxyeremophil-7(11)-ene-12, 8alpha(4beta, 6alpha)-diolide (1), 8beta-methoxyeremophil-7(11)-ene-12, 8alpha(4beta, 6alpha)-diolide (2), petasin (3), isopetasin (4), liguhodgsonal (5), ligudentatol (6), ligujapone (7), lupeol (8) and lupeol palmitate (9).</p><p><b>CONCLUSION</b>Compounds 2, 3, 4, 6, 7 and 9 were isolated from the plant for the first time.</p>